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Post-infectious immune reprogramming and its association with persistence and chronicity of respiratory allergic diseases

PreDicta ended on March 31st 2016

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PreDicta Final Consortium Meeting took place  in Athens March 21st and 22nd 2016          


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Towards serological tests for the identification of RV strains causing asthma exacerbations

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Date of Publication Title 1st Author Title of the periodical or the series
01/05/2016 Antisense molecules: A new class of drugs Potaczek DP et al. Journal of Allergy and Clinical Immunology
01/05/2016 Human Rhinoviruses Enter and Induce Proliferation of B Lymphocytes Aab A et al. Allergy: European Journal of Allergy and Clinical Immunology
01/05/2016 Viruses and bacteria in Th2 biased allergic airway disease Lan F et al. Allergy: European Journal of Allergy and Clinical Immunology
01/03/2016 Increased expression of nuclear factor of activated T cells 1 drives IL-9–mediated allergic asthma Koch S et al. Journal of Allergy and Clinical Immunology
01/02/2016 International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics Jutel M et al. Journal of Allergy and Clinical Immunology
01/02/2016 Mechanisms of Aeroallergen Immunotherapy: Subcutaneous Immunotherapy and Sublingual Immunotherapy Ozdemir C et al. Immunology and Allergy Clinics of North America
13/01/2016 Barrier function of the nasal mucosa in health and type-2 biased airway diseases Zhang N et al. Allergy: European Journal of Allergy and Clinical Immunology
06/01/2016 Rhinovirus inhibits IL-17A and the downstream immune responses in allergic asthma Graser A et al. Mucosal Immunology
23/12/2015 Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1. Lan F et al. Rhinology
04/08/2015 Associations Between Viral and Bacterial Potential Pathogens in the Nasopharynx of Children With and Without Respiratory Symptoms. Skevaki CL et al. Pediatr Infect Dis J
21/11/2015 Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection Schögler A et al. Journal of Cystic Fibrosis
01/11/2015 CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier Kubo T et al. Journal of Allergy and Clinical Immunology
14/08/2015 Association of Mucosal Organisms with Patterns of Inflammation in Chronic Rhinosinusitis. Chalermwatanachai T et al. PLoS One
01/07/2015 Association between respiratory infections in early life and later asthma is independent of virus type Bønnelykke K et al. Journal of Allergy and Clinical Immunology
01/07/2015 T-cell regulation during viral and nonviral asthma exacerbations Wegrzyn AS et al. Journal of Allergy and Clinical Immunology
02/06/2015 Infection with Rhinovirus Facilitates Allergen Penetration Across a Respiratory Epithelial Cell Layer Gangl K et al. International Archives of Allergy and Immunology
01/06/2015 Contributing factors to the development of childhood asthma: working toward risk minimization Guibas GV et al. Expert Review of Clinical Immunology
01/06/2015 Differential Expression and Release of Activin A and Follistatin in Chronic Rhinosinusitis with and without Nasal Polyps. Yang Y et al. PLoS One
15/05/2015 CCL7 and IRF-7 Mediate Hallmark Inflammatory and IFN Responses following Rhinovirus 1B Infection Girkin J et al. American Journal of Immunology
15/05/2015 IL-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations D. J. Jackson et al. Clinical Infectious Diseases
01/04/2015 Challenges in developing a cross-serotype rhinovirus vaccine Glanville N et al. Current Opinion in Virology
25/03/2015 Advances in allergen immunotherapy: Aiming for complete tolerance to allergens C. A. Akdis et al.. Science Translational Medicine
01/01/2015 Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons Gielen, V. EMBO Mol Med.
01/01/2015 T-cell regulation during viral and nonviral asthma exacerbations Agnieszka, S. EBioMedicine
15/12/2014 IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo Jackson, DJ. American Journal of respiratory and critical care medecine
12/11/2014 Rhinovirus-induced VP1-specific Antibodies are Group-specific and Associated With Severity of Respiratory Symptoms Niespodziana, K. EBioMedicine
03/11/2014 Mechanisms of immune tolerance to allergens:role of IL-10 and Tregs Akdis, CA. Journal of Clinical Investigation
01/10/2014 IL-25: The Missing Link Between Allergy, Viral Infection, and Asthma? Andreakos, E. Science Translational Medicine
11/08/2014 Role of Tyk-2 in Th9 and Th17 cells in allergic asthma Ubel, C. Scientific Reports
01/08/2014 Modulation of immune responses by immunotherapy in allergic diseases Cavkaytar, O. Current Opinion in Pharmacology
01/08/2014 The role of macrolides in asthma: current evidence and future directions Sykes, A. BMJ Publishing Group
01/08/2014 SFTA3, a novel protein of the lung: three-dimensional structure, characterisation and immune activation Schicht, M. European Respiratory Journal
01/06/2014 Infantile growth velocity and later asthma/wheeze: GENESIS and the Healthy Growth Study Guibas, G.V. European Respiratory Journal
01/03/2014 The expression of cannabinoid receptor 1 is significantly increased in atopic patients. Fontecha, M. Journal of Allergy and Clinical Immunology
01/03/2014 Mechanisms of allergen-specific immunotherapy: multiple suppressor factors at work in immune tolerance to allergens Akdis, M. Journal of Allergy and Clinical Immunology
01/02/2014 The Common Cold: Potential for Future Prevention or Cure Passioti, M. Current Allergy and Asthma Reports
29/01/2014 IL-15 complexes induce NK cell and T cell responses independent of type I IFN signalling during rhinovirus infection Jayaraman, A. Mucosal Immunology
01/01/2014 The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell–driven immune responses in the setting of allergic asthma Übel, C. Journal of Allergy and Clinical Immunology
01/01/2014 Human bocavirus 1 may suppress rhinovirus-associated immune response in wheezing children Lukkarinen, H. Journal of Allergy and Clinical Immunology
28/11/2013 Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma Mahmutovic-Persson, I. Allergy: European Journal of Allergy and Clinical Immunology
01/11/2013 Physical exercise increases nasal patency in asthmatic and atopic pre-school children Haavisto, LE. American Journal of Rhinology and Allergy
14/10/2013 Rhinovirus-induced interferon production is not deficient in well controlled asthma Sykes, A. Thorax
27/09/2013 Inflammatory patterns in upper airway disease in the same geographical area may change over time Katotomichelakis, M. American Journal of Rhinology and Allergy
26/09/2013 Cross-Serotype Immunity Induced by Immunization with a Conserved Rhinovirus Capsid Protein Glanville, N. PLoS Pathogens
01/09/2013 Conception via in vitro fertilization and delivery by Caesarean section are associated with paediatric asthma incidence Guibas, G.V. Clinical and Experimental Allergy
04/08/2013 Entry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin Pfanzagl, B. Archives of Virology
01/08/2013 An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation Traub, S.L PLoS Pathogens
01/06/2013 Impaired innate interferon induction in severe therapy resistant atopic asthmatic children Edwards, M. Mucosal Immunology
01/05/2013 Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation. Koltsida, O. EMBO Molecular Medicine
30/04/2013 IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy Koch, S. Scientific Reports
19/04/2013 The application of prophylactic antibodies for rhinovirus infections Mclean, GR. Antiviral Chemistry and Chemotherapy
09/03/2013 Microbes and mucosal immune responses in asthma Hansel, T. Lancet, The
01/03/2013 Triggering of specific Toll-like receptors and proinflammatory cytokines breaks allergen-specific T cell tolerance in human tonsils and peripheral blood. Kücüksezer, UC. Journal of Allergy and Clinical Immunology
06/02/2013 γδT cells suppress inflammation and disease during rhinovirus-induced asthma exacerbations Glanville, N. Mucosal Immunology
01/12/2012 Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus Bartlett, N. EMBO Molecular Medicine
01/12/2012 Asthma exacerbations: a molecular dichotomy between antiviral and pro-inflammatory responses revealed Andreakos, E. EMBIO Molecular Medecine
01/12/2012 Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3 Lan, F. Journal of Allergy and Clinical Immunology
01/09/2012 Rhinovirus infections and immunisation induce cross-serotype reactive antibodies to VP1 Mclean, G. Antiviral Research
30/06/2012 "Herpes simplex virus type 1infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasalpolyp tissues" Wang, X. Plos One
25/04/2012 The Genomic Signature of Human Rhinovirus A, B and C. Megremis, S. PLoS ONE
01/03/2012 Misdirected antibody responses against an N-terminal epitope on human rhinovirus VP1 as explanation for recurrent RV infections Niespodziana, K. The FASEB Journal
15/02/2012 Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance Palomares, O. J Allergy Clin Immunol
15/02/2012 Inhibition of angiogenesis by IL-32: Possible role in asthma Meyer, N. J Allergy Clin Immunol
03/06/2011 IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease Andreakos, E. EMBO Mol Med
15/01/2011 Od GA2LEN’a do MeDALL’u – alergologia w europejskich ramowych programach badawczych. Kowalski, M. Biuletyn Informacyjny Uniwersytetu Medycznego w Łodzi